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Examples of macrolides include clarithromycin, erythromycin

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They prevent peptidyltransferase from adding the growing peptide attached to tRNA to the next amino acid as well as inhibiting ribosomal translation. 

They do so by binding reversibly to the P site on the subunit 50S of the bacterial ribosome.

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They prevent peptidyltransferase from adding the growing peptide attached to tRNA to the next amino acid as well as inhibiting ribosomal translation. 

They do so by binding reversibly to the P site on the subunit 50S of the bacterial ribosome.

0 Replies 0 Likes

Macrolides bind reversibly to the P site on the 50S subunit of bacterial ribosome to inhibit protein synthesis.

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