What is the mechanism by which macrolide antibiotics kill bacteria?
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Answer
Lot2Learn
Examples of macrolides include clarithromycin, erythromycin
travisq
They prevent peptidyltransferase from adding the growing peptide attached to tRNA to the next amino acid as well as inhibiting ribosomal translation.
They do so by binding reversibly to the P site on the subunit 50S of the bacterial ribosome.
travisq
They prevent peptidyltransferase from adding the growing peptide attached to tRNA to the next amino acid as well as inhibiting ribosomal translation.
They do so by binding reversibly to the P site on the subunit 50S of the bacterial ribosome.
Lot2Learn
Macrolides bind reversibly to the P site on the 50S subunit of bacterial ribosome to inhibit protein synthesis.